Nate began making videos in 2010. Nate's first videos had quite poor quality and lacked substance. Overtime his videos began to improve in quality - Nate got a better camera, more experience and started putting more effort into his channel.
Ever since Nate started receiving large amounts of hate, he began turning it into comedy by making a series called Dramatic Readings. These include Tobuscus fans, PewDiePie fans, Demi Lovato fans and more. It's basically different YouTubers reading out ridiculous comments made by fans, very dramatically and comically. Dramatic Readings are now one of the main types of videos that Nate's channel has to offer.
Best of NateTalksToYou
One of Nate's two Playlists is called Best of **. It's basically a video that sums up what he has done all year. He has made a best of 2011, 2012 and 2013.
Nate has been making reaction videos as early as 2011, but at some point in late 2012, decided to turn them into a show named WTF Reactions. He got the name from how his brother would shout "what the fuck" while reacting to videos. The videos reacts to vary from bizarre, gross, to just plain disturbing. Earlier reactions usually starred NateTalksToYou, his friends, and/or his brother. However, Nate has started to collaborate with other YouTubers in his reaction videos. His most notable series of reactions would have to be towards pornographic Flash animations of My Little Pony.
Nate also has 2 other channels: NateTalks2You and NateMakesVids. NateTalks2You has mainly been used to upload bonus content related to his main channel, as well as some video projects he's done for school. NateMakesVids features a lot of random content, including short joke videos and archived content.
On November 10, 2012, NateTalksToYou made a review of the song "It's Thanksgiving" by Nicole Westbrook. CNN later did a news report on the song, and included a 3 second clip from Nate's video.